[8] Triptorelin is used to treat prostate cancer as part of androgen deprivation therapy.

[9] Another common use in the United Kingdom is for hormone replacement therapy to suppress testosterone or estrogen levels in transgender people (in conjunction with estradiol valerate for trans women or testosterone for trans men).

[9] Triptorelin has been used as a chemical castration agent for reducing sexual urges in sex offenders.

This causes an initial phase of LH and FSH stimulation, prior to down-regulation of the gonadotrophin-releasing hormone receptors, thereby reducing the release of gonadotropins in the long term, which in turn leads to the inhibition of androgen and estrogen production.

[4] General side effects can include:[4] Triptorelin is marketed under the brand names Decapeptyl (Ipsen) for treating prostate cancer, endometriosis, uterine myomas, and precocious puberty,[13] and Diphereline and Gonapeptyl (Ferring Pharmaceuticals).