The Latin text refers to Christ's Agony in the Garden of Gethsemane, a part of his Passion.
The theme of the text of the second responsory for Maundy Thursday is Jesus in the garden Gethsemane, addressing his disciples.
[1] In the King James Version, the beginning of the Latin text, told in the first person, is translated as "My soul is exceeding sorrowful".
[1] Responsorium:[3] Tristis est anima mea usque ad mortem : sustinete hic, et vigilate mecum : nunc videbitis turbam, quæ circumdabit me.
Versus: Ecce appropinquat hora, et Filius hominis tradetur in manus peccatorum.