Tropatepine (brand name Lepticur) is an anticholinergic used as an antiparkinsonian agent.

[1] Tropatepine can be synthesized from 3-chlorotropane (1).

[2] A Grignard reaction between 3-chlorotropane and dibenzo[b,e]thiepin-11(6H)-one (2) followed by dehydration to the olefin produces tropatepine (3).