Trypanosoma antiquus is an extinct species of kinetoplastid (class Kinetoplastida), a monophyletic[1] group of unicellular parasitic flagellate protozoa.

The genus name is derived from the Greek trypano (borer) and soma (body) because of their corkscrew-like motion, and the species name from antiquua (old) reflecting the age of the specimen.

[2] All trypanosomes are heteroxenous (requiring more than one obligatory host in order to complete life cycle) or are transmitted through some variation of a vector.

The species was described in 2005 by George Poinar Jr. in the journal Vector-Borne & Zoonotic Diseases from metatrypanosomes preserved in several fecal pellets encased in Hymenaea protera amber.

[2] The fossil was recovered in the Dominican Republic from early Miocene Burdigalian stage deposits on the island of Hispaniola.