Found in Brazil and Mexico, it is similar to Trypethelium regnellii, but differs by the presence of anthraquinone crystals in the pseudostromata.

Trypethelium luteolucidum was formally described by the lichenologists André Aptroot, Cléverton de Oliveira Mendonça, and Marcela Eugenia da Silva Cáceres in 2016.

The type specimen was collected in Porto Velho, Rondônia, Brazil, at an elevation of about 100 m (330 ft), on the bark of Hevea brasiliensis in a plantation.

[2] The thallus of Trypethelium luteolucidum is corticate, smooth to somewhat bullate, somewhat shiny, continuous, covering areas up to 10 cm in diameter and approximately 0.2 mm thick.

The upper surface is whitish pruinose or grey to blackish due to the emergent ascomata, and contains crystals inside.