Tsugaru Nobumasa (津軽 信政, August 28, 1646 – December 8, 1710) was the 4th daimyō of Hirosaki Domain in northern Mutsu Province, Honshū, Japan (modern-day Aomori Prefecture).

He was 9 when his father died, and his uncle Tsugaru Nobufusa acted as regent until his coming of age.

In 1660, he completed the construction of a 4.2 kilometer long dam to create Lake Tsugaru-Fushimi for irrigation purposes.

His military forces were called to Ezo by the Tokugawa bakufu in the suppression of Shakushain's revolt, an Ainu uprising against Japanese rule in 1669, and was master-of-ceremonies at the shōgun's pilgrimage to Nikko in 1683.

However, in 1695 a crop failure resulted in famine in the Tsugaru area, and Hirosaki Domain lost 30,000 people.