Results from research conducted by the Atomic Energy Commission of India, in 2011, led the analysts to conclude that this mine might have one of the largest reserves of uranium in the world.

The Bhabha Atomic Research Centre (BARC) has developed an innovative, economically viable process for the recovery of low-grade uranium (less than 0.2%) from the Tummalapalle ore mine.

[13] The hydro-metallurgical uranium purification plant which would be constructed in the mine's current lease period, will treat the dolomite based uraniferous which is found in the deposits.

On the mode of operation, the Uranium Corporation of India report stated that "in the initial period of operation of mine, ore will be received from decline having particle size of 80% passing through 10 cm screen and will be transported by covered dumpers from the mine site to the ore processing plant and later by covered conveyor".

BARC has developed a well-integrated flowsheet for the process to treat the low-grade uranium ore extracted from the alkaline host rocks in Tummalapalle.

[13] Effluents from the plant caused damage to standing crops and polluted groundwater table, when Uranium waste tailing pond brimmed over in the wake of heavy rains in 2021.