Located on the rear wall of the Sant'Antonio Abate church in Pisa, it is one of the last public murals executed before his death from AIDS-related complications in 1990.

Italian university student Piergiorgio Castellani met artist Keith Haring on the streets of the East Village, Manhattan during his winter-break in 1988.

"[1] The mural depicts 30 figures painted in Haring' cartoon-like style with an overarching theme of peace and harmony: "The 'human' scissors are the image of solidarity between Man in defeating the serpent (that is evil), which is already eating the arm of the figure next to it; the woman with a baby in her arms represents maternity, and the two men supporting the dolphin refer to Man's relationship with nature.

"[3] Tuttomondo is often erroneously referred to Haring's last public work, but he created another mural a few months later at the ArtCenter College of Design in Pasadena in November 1989.

For the 30th anniversary of the mural in 2019, they used it on a line of Super Tuscan wines to benefit the artist residency program at Materia Prima.