It featured Gainesville, Florida punk bands such as Psychic Violents, Young Pioneers, Mutley Chix, Doldrums, Just Demigods, Cindy Brady's Lisp, Officer Friendly, and the Smegmas, as well as local speed metal band Hellwitch and avantgarde incidental music by The Bill Perry Orchestra.
Director Charles Pinion went on to make several other underground movies (Red Spirit Lake, We Await and the 2014 3D feature American Mummy).
Twisted Issues was originally intended to be a punk rockumentary featuring Gainesville bands, but the inclusion of writers Steve Antczak and Hawk (James C. Bassett) to the mix added the horror, element to the story, featuring a so-called Death Skater who kills characters played by members of the aforementioned bands after they inadvertently kill him.
In 2011 the exhaustive encyclopedia of punks on film, Destroy All Movies, had a section on Twisted Issues and its director, Charles Pinion.
In 2013, Don Abendroth of The Video Pharmacy released a limited edition (25 copies) of Twisted Issues that included a tiny bloody skateboard and TV set, as well as the soundtrack on cassette, and a new printing of the original booklet.