Two Serious Ladies is a 1943 modernist novel by the American writer Jane Bowles.

It follows two upper-class women, Christina Goering and Frieda Copperfield, as they descend into debauchery.

[2] In February 2012, an online magazine of the same title was created to honor Bowles' legacy and to promote writing by women.

[3] In issue 543 of Interview magazine, filmmaker John Waters said he loves Jane Bowles and that "Two Serious Ladies" is the best novel ever written.

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