White started 2015 with the Corpus Christi Hooks and was later promoted to the Fresno Grizzlies of the Triple–A Pacific Coast League.

In 2017, White spent most of his time in the Minors, but still played 22 games with the Astros, compiling a .279 batting average, 3 home runs, and 10 RBI.

[6] In 2018, White spent time in Fresno and Houston, serving as first baseman and designated hitter for the Astros.

[7] On May 7, 2019, in a blowout from the Kansas City Royals, White pitched a scoreless ninth inning, giving up one walk and striking out Chris Owings in the process.

On June 16, 2019, White pitched for the 3rd time on the season against the Toronto Blue Jays in another blowout loss.

The name was originally bestowed upon him by Josh Innes, but came to mainstream popularity when on August 28, 2018, White hit a walk off homerun against the Oakland A's.

Steve Sparks, of the Houston Astros Radio Network, referred to White as "Big Puddin'.

[12] On August 29, 2018 Sportstalk 790 (KBME (AM)), via twitter, asked Astros fans to vote for Tyler White's nickname.

On December 15, 2020, White signed a minor league contract with the Toronto Blue Jays organization and was invited to Spring Training.

[21] On August 16, 2022, White was traded to the Atlanta Braves in exchange for cash considerations and assigned to the Triple-A Gwinnett Stripers.