[5] Zuber made his major league debut on July 24, 2020 against the Cleveland Indians, pitching 2 scoreless innings.

With the 2020 Kansas City Royals, Zuber appeared in 23 games, compiling a 1-2 record with 4.09 ERA and 30 strikeouts in 22.0 innings pitched.

[6] Zuber was placed on the 60-day injured list to begin the 2022 season on March 16, 2022, due to right shoulder impingement syndrome.

After returning from his shoulder injury, Zuber made 16 appearances for Reno and posted a 5.23 ERA with 18 strikeouts in 20+2⁄3 innings pitched.

On April 23, 2024, Zuber signed with the Long Island Ducks of the Atlantic League of Professional Baseball.