Tylomelania is a genus of freshwater snails which have an operculum, aquatic gastropod mollusks in the family Pachychilidae.

A sister group (the closest relative) of Tylomelania is genus Pseudopotamis (2 species living on the Torres Strait Islands).

[5] Tylomelania are endemic to Sulawesi in Indonesia,[2] with the vast majority restricted to Lake Poso and the Malili Lake system (consisting of Matano and Towuti, and the smaller Lontoa (Wawantoa), Mahalona, Masapi).

Tylomelania species diversification started in c. 5.4 Mya and was probably caused by the late Miocene and Pliocene orogeny.

[2] The pallial oviduct evolved into a uterine brood, which releases shelled juvenile snails.