This species occurs in Lake Towuti and in the Tominanga River, in south Sulawesi, Indonesia.
[2] Its type locality is lake Towuti, Loeha Island.
[3] The females of Tylomelania towutica usually have 1-7 embryos in their brood pouch.
[3] Newly hatched snails of Tylomelania towutica have a shell height of 0.5-9.3 mm.
[3] It is a part of ornamental pet trade for freshwater aquaria.