When his girlfriend's family temporarily takes over his Manhattan apartment, Tyler, a young Black man, agrees to join his friend Johnny for a guys' weekend of debauchery in the Catskill Mountains.

In March 2017, it was announced Sebastián Silva would write and direct the film, with Michael Cera, Caleb Landry Jones, Jason Mitchell, Christopher Abbott, and Roddy Bottom set to star.

The website's critics consensus reads: "Tyrel uses its seemingly innocuous setup to take an admirably uncomfortable -- albeit occasionally somewhat diffuse -- look at modern American race relations.

Chris Nashawaty of Entertainment Weekly said, "It's both unavoidable and a bit unfair to compare writer-director Sebastian Silva's squirm-inducing new indie Tyrel to last year's Get Out.

Dennis Harvey of Variety said "this lively, unpleasant seriocomedy...does very well at capturing the queasiness of being alone and uneasy at a party you immediately know you won't fit into",[4] while David Fear of Rolling Stone called it "a character study, racial satire, and horror movie all in one.

"[14] Fear added, "Viewers are both complicit in Tyler's breakdown — the look of self-contempt on his face after he's pressured to imitate an elderly black woman feels like a slap to ours — and right there with him as he goes deeper into a nightmare fueled by tone-deaf idiocy and too much Irish coffee.

"[15] Writing for The New York Times, Bilge Ebiri commented that the film takes on a more "surreal" tone with Michael Cera's appearance, but said, "the stranger Tyrel gets, the more accurate it feels.

"[16] Critics also noted how the depictions of characters Nico and Dylan, who are Argentinian and gay, respectively, show how "something so theoretically nice as intersectional solidarity is not necessarily on the table here.