Tyszowce (Polish: [tɨˈʂɔft͡sɛ]; Yiddish: טישעוויץ, romanized: Tishevitz) is a town in Tomaszów Lubelski County, Lublin Voivodeship, in south-eastern Poland, with 359 inhabitants (2004).

The history of Tyszowce dates back to the Middle Ages, when a gord probably existed among swampy meadows of the Huczwa river.

In 1500, Tyszowce was destroyed in a Crimean Tatar raid; the destruction was so widespread that for the next 10 years no taxes were collected.

In the early 17th century, Tyszowce was raided by Tatars, and in 1649, the town was destroyed during the Khmelnytsky Uprising.

On December 29, 1655, the Tyszowce Confederation was signed here, with the purpose of pushing Swedes out of Poland, and bringing back King John II Casimir Vasa.

In 1767, Tyszowce became private property, and five years later, following the First Partition of Poland, the town was annexed by the Habsburg Empire, as part of Austrian Galicia.

In 1869, Russian authorities stripped Tyszowce of its town charter, as a revenge for widespread support of the uprising.

During the night of April 16, 1942, SS troops, Gestapo and German police launched a massive execution of Jews in Tyszowce.