[9] Bowser missed five games his senior season due to a fractured orbital bone that he suffered during a fight with a teammate.

Bowser also participated at Houston's Pro Day and chose to only run the short shuttle and positional drills.

NFL draft experts and analysts projected Bowser to be a first or second round pick.

[20][21] The Baltimore Ravens selected Bowser in the second round with the 47th overall pick in the 2017 NFL draft.

[26] He recorded his first NFL interception in Week 2 against quarterback Kevin Hogan of the Cleveland Browns, returning it for 27 yards and setting up a critical touchdown by the Ravens' offense before halftime.

[29] In Week 10 of the 2019 season, Bowser recorded a 33-yard fumble return for a touchdown in the 49–13 victory over the Bengals.

[36] In the final seconds in the fourth quarter Bowser sacked Andy Dalton for a loss of 18 yards, which yielded a 16–13 win over the Chicago Bears on November 21, 2021.

[37] The following week, against the Browns, Bowser recorded a sack on Baker Mayfield, as well as a game sealing tackle on fourth down in the 16–10 victory.

[38] Bowser finished the 2021 season with seven sacks, 59 total tackles, four passes defended, and two forced fumbles.