[3] During the years 1832–6, Diplomat Edmund Roberts was appointed by President Andrew Jackson as America's first envoy to the Far East, and served on two consecutive non-resident embassies aboard the U. S. Navy sloop-of-war Peacock to the court of King Nangklao (Rama III of the Kings of Thailand.)

Roberts negotiated the Treaty of Amity and Commerce between Siam and the United States of 1833 and returned in 1836 to exchange ratifications.

Other important agreements address civil uses of atomic energy, sales of agricultural commodities, investment guarantees, and finally military and economic assistance.

[12][13][14] Since the military coup of May 2014, relationships between Thailand and the United States have experienced strains, with several ultra-nationalist demonstrations in front of the U.S. Embassy on Wireless Road, and even charges alleged against the U.S. ambassador for lese majeste.

[15] Designed by New York firm SHoP Architects, the NOX will be built to LEED Silver Certification and incorporate traditional Thai architectural elements.