From here, US 6N continues south, narrowing to a two-lane undivided road and crossing under the Canadian National Railway's Bessemer Subdivision railroad line before running through forested areas with some fields and homes.

PA 18 splits from US 6N in Wellsburg by heading to the north, and US 6N continues east through areas of farms and woods with some homes.

Past this interchange, US 6N becomes a two-lane undivided road again passes through more rural surroundings before heading into more residential areas and entering the borough of Edinboro.

The route turns east into the commercial downtown, gaining a center left-turn lane, and intersects PA 99.

The route continues back into Washington Township and curves northeast through agricultural areas with some residential and commercial development.