[6] The highway passes through Kingman, Arizona; Las Vegas, Nevada; Twin Falls, Idaho; and Missoula, Montana.

US 93 exits at the Las Vegas Spaghetti Bowl interchange just northwest of downtown, heading northbound concurrently with Interstate 15 (I-15).

Upon reaching Lages Station, U.S. Route 93 Alternate (US 93 Alt) splits off in a northeasterly direction toward West Wendover.

Shortly after entering Idaho, US 93 crosses U.S. Route 30 as it before running through the northern edge Twin Falls.

North of here, the highway crosses the Snake River Canyon via the Perrine Bridge en route to an interchange with Interstate 84.

The highway then turns northwest (leaving US 20 / US 26) to enter the Big Lost River valley through Mackay.

[10] From there, the highway follows portions of the Lewis and Clark Trail and passes through the Salmon-Challis National Forest before entering Montana.

US 93 enters Montana from Idaho at Lost Trail Pass and travels north descending through the Bitterroot National Forest.

The highway continues along the Lewis and Clark Trail into the Bitterroot Valley towards Missoula, passing through Darby and Hamilton.

At Lolo, U.S. Route 12 (US 12) joins from the west and they run concurrently northeast for 7.537 miles (12.130 km), where US 93 heads due north on Reserve Street in Missoula.

From Wye, US 93 continues north through the Flathead Indian Reservation, where its signage includes the historic Salish and Kutenai names for towns, rivers, and streams.

[citation needed] However, the revised numbering plan approved by the American Association of State Highway Officials (AASHO) on November 11, 1926, established US 93 from the Canada–US border north of Eureka, Montana, south through Montana and Idaho to a southern terminus at Wells, Nevada.

[15] At the request of the Arizona State Highway Department, the AASHO route numbering committee approved another extension of US 93 in 1935.

The bypass eliminated the permanent truck detour through either Laughlin, Nevada, or Needles, California, that had been in place since 2001.

US 93 (with US 60 to the southeast of Wickenburg) is currently the shortest and most direct route between Las Vegas and Phoenix, two of the fastest-growing cities in the United States.

US 93 (Highway 93) features in the title track from Montana Cafe, a studio album by American country music artist Hank Williams Jr., released by Warner Bros. Records in July 1986.

Metal band Avenged Sevenfold included the stretch of US 93 between Kingman and Wickenburg, in Arizona, in the music video for their song, "Dear God".