The women's, boys' and girls' basketball tournaments were not held this season, also due to the pandemic.

The SM Mall of Asia Arena in Pasay hosted the opening ceremonies and all the games.

[16] However, on April 5, 2022, which was the fifth playing date of the basketball tournament, the UAAP allowed fans in a limited capacity to watch live at the Mall of Asia Arena.

This is the first meeting between UP and La Salle in the semifinals (and playoffs stages) in UAAP men's basketball history.

La Salle returned to the semifinals for the first time since 2017 after missing out in the past two tournaments.The finals is a best-of-three series.