2A4D, 2C2V, 2HLW733566589ENSG00000244687ENSMUSG00000078923Q13404Q9CZY3NM_001257397NM_001257398NM_001257399NM_001282575NM_001282576NM_001282577NM_001282578NM_001282579NM_001282580NM_021988NM_022442NM_199144NM_023230NM_001311131NM_001311146NP_001244326NP_001244327NP_001244328NP_001269504NP_001269505NP_001269506NP_001269507NP_001269508NP_001269509NP_068823NP_071887NP_954595NP_954673NP_001298060NP_001298075NP_075719Ubiquitin-conjugating enzyme E2 variant 1 is a protein that in humans is encoded by the UBE2V1 gene.

They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s.

The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene.

It is thought to be involved in the control of differentiation by altering cell cycle behavior.

Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene.