UFC 253: Adesanya vs. Costa was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on September 27, 2020 at the du Forum on Yas Island, Abu Dhabi, United Arab Emirates.

[10] A UFC Middleweight Championship bout between former champion Israel Adesanya and Paulo Costa served as the event headliner.

[14] Former two-time champion Jon Jones vacated the belt on August 17, citing issues with the UFC over salary negotiation and the desire to compete at heavyweight.

[19] In late August, the bout was moved from this event to UFC Fight Night: Covington vs. Woodley a week earlier.

[22] A flyweight bout between Jordan Espinosa and David Dvořák was expected to take place at this event, but was later rebooked for UFC Fight Night: Covington vs. Woodley due to undisclosed reasons.

Both of their bouts proceeded at a catchweight and they were each fined a percentage of their individual purses, which went to their opponents Hakeem Dawodu and Shane Young.