UFC 276: Adesanya vs. Cannonier was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on July 2, 2022, at the T-Mobile Arena in Paradise, Nevada, part of the Las Vegas Metropolitan Area, United States.

[3] A UFC Middleweight Championship bout between current champion Israel Adesanya and Jared Cannonier headlined the event.

They were originally expected to meet for the third time at UFC 272, but Holloway withdrew due to an aggravated previous injury.

[13] The pairing was originally scheduled to meet as UFC on ESPN: Luque vs. Muhammad 2 but Hall withdrew for unknown reasons.

[21] In turn, Green withdrew again for unknown reasons and was replaced by former UFC Lightweight Championship challenger Donald Cerrone in a welterweight bout.