UFC 278: Usman vs. Edwards 2 was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on August 20, 2022, at Vivint Arena in Salt Lake City, Utah, United States.

[2] The event marked the promotion's second visit to Salt Lake City, following UFC Fight Night: Rodríguez vs. Caceres in August 2016.

[9] A women's flyweight bout between Miranda Maverick and Shanna Young was scheduled for the event.

[10] However, the bout was cancelled on the day of the weigh-ins as Young was hospitalized due to weight cut issues.

The amounts do not include sponsor money, discretionary bonuses, viewership points or additional earnings.