However, Gastelum was pulled from the bout after he tested positive for Carboxy-Tetrahydrocannabinol (Carboxy-THC) which is a metabolite of marijuana or hashish above the 180 ng/mL allowance by the World Anti-Doping Agency (WADA) standard.

[5][6] On November 10, it was announced that Silva had failed an out of competition drug test stemming from a sample collected on October 26 and as a result had been pulled from the card.

[7] A day later, former UFC Middleweight Champion and The Ultimate Fighter 3 light heavyweight winner Michael Bisping was secured as a replacement opponent for Gastelum.

[13] [14] The following fighters were awarded $50,000 bonuses:[15] On January 30, 2018, it was announced that Mulheron accepted a one-year suspension due to his failed test.

[17] On July 18, Silva was suspended for one-year, retroactive to November 10, 2017, after USADA traced his second positive drug test to a compounding pharmacy known for producing tainted supplements.