UFC on ABC: Ortega vs. Rodríguez (also known as UFC on ABC 3) was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on July 16, 2022, at UBS Arena in Elmont, New York in the United States.

[5] The pair was previously scheduled to meet at UFC on ESPN: Hall vs. Strickland in July 2021, but Askarov pulled out citing injury.

[6] Askarov pulled out once again in early June due to undisclosed reasons and Perez was rescheduled against Alexandre Pantoja at UFC 277.

[8] However, Fortino withdrew in early June for unknown reasons and was replaced by another former Invicta FC Strawweight Champion in Emily Ducote.

[13] A couple of featherweight bouts featuring Bill Algeo vs. Billy Quarantillo and Herbert Burns vs. Khusein Askhabov were scheduled for this event.