[5] Ashley Yoder was expected to face Vanessa Demopoulos in a women's strawweight bout at the event.

[6] Yoder eventually withdrew due to undisclosed reasons and was replaced by Silvana Gomez Juarez.

[12] However, in early January 2022, it was reported that the bout was canceled as Rodrigues has tested positive for influenza (H3N2) and Adashev has suffered an injury.

[17] Three days before the event, Benitez was forced to pull out and Charles Rosa replaced him, therefore changing the contest to the lightweight division.

[19] However, Kakhramonov withdrew from the bout due to undisclosed reasons and was replaced by Kevin Croom, shifting the contest to the featherweight division.