The team played in the regional leagues for the vast majority of its first 26 years, with the one exception being a season-long stay in Tercera División in 1967–68.

The team returned to the category, now the national fourth division, twenty-one years later, remaining there for the subsequent decades.

In 1991–92 and the following campaigns it was crowned division champions, adding four runner-up places; however, none of the ten promotion playoff visits to Segunda División B was successful.

On 28 September 2017, Escobedo achieved its first regional tournament by winning the Cantabrian stage of the Copa Federación after beating Cayón by a huge 3–0 in the final.

[3] Escobedo's home ground is the Estadio Eusebio Arce, around a mile west of Muriedas, the capital of Camargo.