1049722249ENSG00000198722ENSMUSG00000028456O14795Q9Z1N9NM_001371189NM_001387551NM_001387553NM_001387554NM_001387555NM_001081413NM_021468NM_001310758NP_001358118NP_001074882NP_001297687NP_067443NP_001371035Protein unc-13 homolog B is a protein that in humans is encoded by the UNC13B gene.

[5][6] This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia.

Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia.

Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.

This article on a gene on human chromosome 9 is a stub.