In 1994, as the Commander of Operation Able Manner forces, she directed the rescue of thousands of Haitian and Cuban migrants flowing across the Windward Passage and Florida Straits toward U.S. shores.

Most recently, exhibiting the Coast Guard's multi-mission nature and typical of Harriet Lane's twenty years of service, she stood as a maritime security sentry in Charleston, South Carolina Harbor for the Operation Iraqi Freedom load-out, then moved south to the Caribbean and seized two tons of cocaine headed for the U.S., and finally, rescued several hundred migrants attempting to reach the U.S. in unseaworthy boats.

[1] Harriet Lane completed a 15 month, $21 million Service Life Extension Program at the Coast Guard Yard in Baltimore on 3 August 2023.

[2] In mid-December 2023, Harriet Lane arrived in her new home port of Honolulu, Hawai'i to begin work as part of U.S. Coast Guard District 14.

She joined 11 ships from 10 countries in Nuku’alofa including Australia's HMAS Choules, China’s PLA-N Zibo, Japan’s JS Noshiro, New Zealand’s HMNZS Manawanui, UK's HMS Tamar, with Tonga's VOEA Ngahau Koula serving as the King's flagship.