While en route, the ship developed leaks in the tubes of one boiler and, upon her arrival at Manus on 9 November, made repairs.

The transport then proceeded to Nouméa, New Caledonia, to embark Army troops for training exercises in preparation for landings on Luzon, Philippine Islands.

Audrain participated in two combat operations, the landings at Lingayen Gulf (9 January 1944) and the massive invasion of Okinawa (1 to 9 April 1945).

She discharged these passengers and their gear on secured beaches in the San Jose area of Mindoro on 9 February and retired to Leyte Gulf.

She arrived off that island on D day, 1 April, began lowering her boats, and sent them to other transports to assist in landing their assault troops.

On 6 June, Audrain opened fire on a lone Japanese Aichi D3A "Val" bomber, but scored no hits.

However, two 40-millimeter projectiles fired by neighboring vessels hit her on the forward bulkhead of the navigation bridge, slightly wounding three members of her crew.

The ship paused at Guam on 14 April to transfer casualties from Okinawa to hospitals ashore, and then she continued on to Pearl Harbor.

Audrain left California, sailed back to Hawaii in early April, and remained in port at Pearl Harbor for the duration of her naval career.

Audrain was decommissioned at Pearl Harbor on 15 May 1946, and transferred to the Maritime Commission 25 July 1947, for laying up in the National Defense Reserve Fleet at Suisun Bay, California.

Her name was struck from the Navy list on 1 August 1947, and the ship was sold for scrap 11 July 1972 to the National Metal & Steel Corporation of Terminal Island, California.