USS Carlisle (APA-69) was a Gilliam-class attack transport that served with the United States Navy from 1944 to 1946.

Carlisle cleared San Diego 23 January 1945, carrying sailors, Marines, and general cargo to Pearl Harbor.

Between 2 April and 5 June, she had duty training and transporting Marine units among the islands of the Hawaiian group.

Carlisle made three voyages to the west coast from Hawaii and Japan, and shorter passages among South Pacific islands, redeploying servicemen until 4 February 1946.

Carlisle was decommissioned at Bikini Atoll and struck from the Navy Register, both dates unknown.