Along the way, she transited the Panama Canal and made stops at Pearl Harbor and Guam before reaching her base of operations at Subic Bay in the Philippines on 24 February.

She entered port at Danang, South Vietnam, on 5 March and, the following day, was on her way for a PIRAZ (Positive Identification Radar Advisory Zone) station.

For the next four months, Biddle alternated between periods at sea—either carrying out PIRAZ duty, serving as an antiair warfare (AAW) picket, or acting as a sea-air rescue (SAR) vessel—with time in port at Subic Bay or Yokosuka, Japan.

During the voyage, she completed a circumnavigation of the world and visited such diverse places as Singapore, Lourenco Marques (now Maputo) in Mozambique, the Cape Verde Islands, Lisbon in Portugal, and Copenhagen in Denmark.

Returning to the Hampton Roads area, she loaded missiles, torpedoes, and ammunition at Yorktown, Virginia, on 30 April before reentering Norfolk on 1 May.

Between the 2d and the 6th, Commander, Destroyer Squadron (ComDesRon) 3, rode in Biddle and served as antiair warfare coordinator for Task Force (TF) 77.

The guided-missile frigate departed Hong Kong on 4 November, made a fuel stop at Subic Bay, and then headed back to Vietnam.

She arrived back in the Gulf of Tonkin on 7 November and spent the next six days serving as plane guard for the aircraft carrier Coral Sea.

After a brief fuel stop at Guam and a three-day liberty call at San Francisco, California, Biddle arrived in the Canal Zone on 16 December.

On 13 April, the guided-missile frigate stood out of Norfolk on a five-week cruise to the Caribbean for training and for technical evaluation of her new and modified radar equipment.

In March, she entered the Norfolk Naval Shipyard to be modified to carry a LAMPS (Light Airborne Multi-Purpose System) helicopter.

Biddle spent over a month on station operating as a SAR picket and directing antiair warfare before returning to Subic Bay on 26 June.

On 19 August, the United States ambassador to Cyprus was assassinated; soon thereafter, Biddle joined a special task group off the island to assist in the event of an evacuation of American citizens.

The main feed pump in the forward engine room failed catastrophically, which caused the port propeller to suddenly stop.

After five days at Civitavecchia, Italy, for liberty in Rome, Biddle got underway for the eastern Mediterranean and a transit of the Straits of Bosporus and the Dardanelles.

During the ensuing four months, Biddle conducted post-overhaul tests, drills, and refresher training along the east coast and in the West Indies.

At the end of those maneuvers, Biddle made port visits at Hamburg in Germany, Antwerp in Belgium, and Cherbourg in France before getting underway for home on 29 October.

That deployment brought visits to ports throughout the Mediterranean basin and a variety of training missions, often conducted in company with units of Allied and friendly navies.

At sea, the warship ranged from the New England coast south to the West Indies participating in multiship exercises, conducting independent ship's drills, and making missile and gun shoots.

After about a month of 6th Fleet operations and port visits, Biddle transited the Straits of the Bosporus and the Dardanelles and entered the Black Sea once again.

She resumed normal 6th Fleet operations, conducting multiship drills and exercises and making goodwill visits to ports in the Mediterranean.

By mid-July, she was on PIRAZ station in the eastern Mediterranean with the contingency force supporting Marine Corps troops ashore in Lebanon.

Between 21 and 28 August, she served as escort for Palestinian Liberation Organization refugees leaving Beirut for Tunisia on board the Cypriot merchantman SS Sol Phryne.

That employment lasted until 14 October when she began a selected restricted availability at the Norfolk Shipbuilding Co. Those repairs occupied her time for the remainder of 1983.

During a port visit in early January 1986 at Diego Garcia, British Indian Ocean Territory, the battle group was informed that they needed to get underway on very short notice.

The 5th patrol off Libya now included Operation El Dorado Canyon, the aerial attacks on Tripoli and terrorist camps near Benghazi.

USS Biddle was deployed to the Middle East in September 1990 as part of Operation Desert Shield, where she joined the Saratoga battle group at the Red Sea.

The US Navy flew a replacement rudder, via USAF C-5B aircraft to Toulon, France, where repairs were effected at the French Naval Shipyard.

[3] After spending Christmas at Toulon, France, Biddle rejoined the operations, this time to provide antiaircraft support for the two US battle groups on station in the northern Red Sea.

[4] The cruiser was decommissioned and stricken from the Naval Vessel Register on 30 November 1993 and sold for scrap to Metro Marine Corporation of Philadelphia on 4 December 2000.