Following shakedown training off New London, Connecticut, and Newport, Rhode Island, Blueback got underway on 2 October 1944 for Key West, Florida.

On 16 December 1944, Blueback departed Pearl Harbor to commence her first war patrol in company with the submarine Puffer.

The three submarines formed a coordinated attack group which was patrolling north of Saipan in the Mariana Islands on 27 December 1944 when a United States Army Air Forces B-24 Liberator bomber crashed into the sea a few thousand yards [meters] away from the American submarines, and Blueback rescued four of the bomber's crewmen.

On 26 January 1945, she left the area and headed southwest into the South China Sea to patrol off Camranh Bay on the coast of Japanese-occupied French Indochina.

On 4 February 1945, Blueback spotted a Japanese convoy heading south toward Camranh Bay and immediately tried to close for an attack but was unable to get near enough to fire her torpedoes.

She began lifeguard duties in support of Allied airstrikes on 7 February, taking station 200 nautical miles (370 km; 230 mi) to the southeast of Camranh Bay on the Hong Kong-to-Singapore sea route.

Over the next three days, she took part in a search for a Japanese battleship task force headed north from Singapore but never detected it.

Operating in a coordinated attack group with the submarines Bergall, Blackfin, Hawkbill, and Flasher, Blueback began her second war patrol on 4 March 1945 and headed for the area in the South China Sea off the coast of French Indochina.

On 27 March 1945, an Allied search plane reported a Japanese convoy to the south of Blueback's coordinated attack group.

She patrolled off Sumbawa and Lombok in the Japanese-occupied Netherlands East Indies until 12 April without making any contacts and then headed for Australia.

She concluded her patrol at Fremantle, Australia, on 17 April 1945 and commenced a refit alongside the submarine tender USS Clytie (AS-26).

On 26 June 1945, Blueback entered Lombok Strait and received a contact report on Japanese ships sighted north of Bali.

During her upkeep and training at Subic Bay, World War II came to an end on 15 August 1945 with the cessation of hostilities with Japan.

On 10 July 1945, while in the Java Sea, Ensign John Thomas Beahan, a gunnery officer, was inspecting a .50-caliber gun on the deck of the USS Blueback (SS 326) when it unexpectedly fired two rounds, fatally striking him in the chest.

[citation needed] On 31 August 1945, Blueback got underway from Subic Bay bound for Guam in the Mariana Islands, where she arrived on 4 September 1945.

Her ports of call included Pearl Harbor, Truk in the Caroline Islands, Subic Bay, and Tsingtao and Shanghai in China.

On 4 March 1948, Blueback departed San Diego and, after a stop at Naval Submarine Base New London in Groton, Connecticut, proceeded across the Atlantic Ocean and the Mediterranean Sea to İzmir, Turkey, where she arrived on 11 May 1948.

[9] After long service in the Turkish Naval Forces, İkinci Inönü was decommissioned and transferred back to the United States on 30 November 1973.