Boyle joined the Atlantic Fleet and sailed from Norfolk, Virginia 25 October 1942 as part of Task Force 34 (TF 34), bound for the invasion of North Africa.

[2] The monotony of convoy duty was broken by participation in the Sicilian invasion, where she served as a guide ship for the Scoglitti landings (9–15 July 1943).

Following a yard period at Boston, Massachusetts, she returned to the Mediterranean 21 December 1944 and remained there on fire support and escort duty until 22 April 1945.

After cruising between San Diego and Pearl Harbor (25 June–17 July 1945) she steamed to the western Pacific, arriving at Saipan 5 August.

She arrived off Tokyo 11 September and served in Japanese, Okinawan, and Chinese waters until departing Okinawa 1 November.