Brule joined Transport Squadron 16 and departed San Pedro 26 November 1944 for Pearl Harbor.

From April 1945 until the cessation of hostilities Brule carried troops and supplies between various bases in the Bonins, Marianas, Marshalls, Philippines, and Solomons.

In November 1945 Brule became a unit of the Operation Magic Carpet fleet, tasked with bringing returning servicemen home from the war.

While at Yokosuka, during one of her voyages, Brule was ordered to prepare for assignment to the target fleet for Operation Crossroads, the atomic bomb tests at Bikini Atoll.

This article incorporates text from the public domain Dictionary of American Naval Fighting Ships.