Cyane was a Royal Navy sailing Banterer-class sixth-rate ship of 22 guns, built in 1806 at Topsham, near Exeter, England.

She was ordered in January 1805 as HMS Columbine and was renamed Cyane on 6 December of that year.

She was captured with HMS Levant on 20 February 1815 by USS Constitution after a 40-minute night engagement off Madeira.

With Constitution's second lieutenant Hoffman as prize master, she successfully escaped recapture by a pursuing British squadron on 12 March and arrived in America on 10 April.

Laid up at Philadelphia Navy Yard, she sank in 1835 and was raised and broken up the following year.