In addition, she took part in the regular schedule of training operations along the east coast and in the Caribbean where in 1948 she rescued 10 men from a small coastal freighter sinking in the Windward Passage.

On 3 January 1951, Fiske sailed from Newport for the Panama Canal and the Far East, reporting on 12 February to the 7th Fleet at Sasebo, Japan for duty in the Korean War.

Along with screening carrier task forces, she patrolled off Korea, joined in bombarding shore targets, and escorted shipping from Japan to the action areas.

Recommissioned 25 November 1952, Fiske trained with her new equipment in preparation for her participation in the fall of 1953 in NATO Operation "Mariner," which took her north of the Arctic Circle.

Her training operations when assigned to the 2nd Fleet for duty in the western Atlantic and Caribbean included special work in development of anti-submarine warfare, and air defense.

Homeported at Mayport, Florida, from August 1960, Fiske joined in NATO exercises north of the Arctic Circle in the fall of 1960, and at the close of the year, sailed for patrol duty in the Caribbean.

On the evening of her arrival back home, and without her full crew, she was ordered to rendezvous with the Enterprise (CVAN-65) in the Windward Passage as the Soviets were challenging the United States in the Cuban Missile Crisis.

Fiske spent approximately one month patrolling the entrance to Santo Domingo Harbor, earning the Armed Forces Expeditionary Medal for her efforts.

A relaxed leave and liberty policy was the rule for the next six months as crew changes were made prior to the "Acey Deucy Squadron" (DesRon 12) deploying to Vietnam.

DesRon 12 then visited San Diego Naval Station for approximately eight hours on 5 February to pick up equipment, then got underway for Hawaii.

After five days in Hawaii, DesRon 12 got underway for the Philippine Islands, crossing the International Date Line on 18 February, as the crews entered the Realm of the Golden Dragon.

The remainder of March, 1966 was spent as escort and plane guard for the Ranger (CVA-61), and the Enterprise (CVA(N)-65) on "Yankee Station" off the "I Corps Operational Area".

Detached from escort duties on 1 April, Fiske entered the Gulf of Tonkin for duty as a Search and Rescue (SAR) ship, answering the first SAR call on 2 April, an operation involving a pilot and a rescue helicopter from Enterprise, though unable to assist, the helicopter with pilot aboard cleared North Vietnamese airspace en route to the Enterprise.

On 6 June, Fiske relieved Davis (DD-937) of Naval Gunfire Support (NGFS) duties and escorted a truck convoy along the Coast Highway approximately 50 miles south to Da Nang, on her fourth War Patrol.

17 June found the Fiske supporting the 2nd Battalion, 4th Division, U.S. Marines in "Operation Dodge" in the area of the ancient Vietnamese capital of Huế.

The mission was cancelled at the last minute, but not before some hands witnessed nighttime "Arc Light" B-52 raids, and "Puff" firing its Gatling guns from the air to the ground in the area of the Mekong River delta.

Departing Subic Bay on the 6th, Fiske entered the Combat Zone for the sixth and final War Patrol, a short stint as a part of "Operation Market Time".

As Fiske crossed the Equator at Longitude 106 degrees, 27 minutes East, in the Singapore Strait, the segment of the crew that heretofore had never crossed the equator received justice from those who had: the "Shellbacks", and were mercifully, and most ceremonially converted from "Pollywogs" to "Shellbacks" after suffering the pains and torments required when entering the realm of King Neptune himself.

DesRon 12 headed west, with stops at Penang, Malaysia, then Cochin, India, and Aden Protectorate, British Crown Colony, through the Red Sea (complete with a desert sandstorm), and the Suez Canal.

They included Djibouti, French Somaliland; Massawa, Ethiopia; Bahrain; Karg Island, Madagascar; Diego-Suarez, and Mombasa, Kenya.

These plans were quickly changed when the carrier USS Forrestal suffered numerous explosions and fires on 29 July 1967 while operating in Vietnam.