Furse sailed from Norfolk, Virginia on 7 November 1945 for occupation duty in the Far East, calling at San Diego, California and Pearl Harbor en route to Tokyo Bay, where she arrived on 22 December.

The destroyer returned to San Diego on 12 August 1946, and until her transfer to the Atlantic Fleet in April 1949, operated on training along the west coast, and completed another tour of duty in the Far East.

Among the highlights of the destroyer's operations were visits to ports of northern Europe between September 1950 and December, during which she represented the United States at the funeral of King Gustav V of Sweden.

The next year, she made two tours of duty in the Mediterranean because of the tense political situation prevailing, and in the summer of 1958, she sailed for NATO operations in northern waters, visiting Santander, Spain; Stavanger, Norway; and Ghent, Belgium.

In the winter of 1967, Furse spent time in the Boston Naval Shipyard receiving her regular yard overhaul period in preparation for a WESTPAC cruise in the summer of 1968.

Captained by Michael T. Greeley USN, Furse operated with the Seventh Fleet in the Tonkin Gulf, including the recommissioned battleship USS New Jersey (BB 62).