From Newport, Forrest Sherman sailed on training and fleet exercises along the east coast and in the Caribbean, until the summer of 1957, when she took part in the midshipman cruise to South America and the International Naval Review in Hampton Roads on 12 June.

During the summer of 1959, Forrest Sherman joined in Operation Inland Seas, the cruise of a task force into the Great Lakes in celebration of the opening of the St. Lawrence Seaway.

She served as escort to the Royal Yacht HMY Britannia with President Dwight D. Eisenhower and Queen Elizabeth II embarked, then sailed on to entertain over 110,000 visitors at Great Lakes ports.

Returning to Newport, Forrest Sherman took part in coastal exercises with the Atlantic Fleet, then underwent minor repairs and alterations in the Boston Naval Shipyard.

Forrest Sherman was decommissioned on 5 November 1982, stricken from the Naval Vessel Register on 27 July 1990 and sold for scrap to the Fore River Shipyard and Iron Works at Quincy, Massachusetts, on 11 December 1992.