General Meigs made two similar round-trip voyages from the United States to Italy and North Africa via Brazil, carrying thousands of American and Brazilian troops to Europe for the remaining drive against Nazi Germany, and returning several thousand others to the United States and Brazil.

From Le Havre, Naples, Marseilles, Karachi, and Nagoya, she made six more trips carrying homebound troops for New York and Brazil.

On 4 March 1946, she was decommissioned at San Francisco for transfer to the American President Lines as a passenger ship in the Pacific.

Crewed by civilians, she made 19 cruises to the Far East carrying thousands of American troops from the West Coast to ports in Japan and South Korea.

Placed in Reduced Operational Status in 1955, she was transferred to the Maritime Administration on 1 October 1958, and entered the National Defense Reserve Fleet at Olympia, Washington.