During almost the next 9 months she sailed the Southwest Pacific, carrying cargo and rotating troops from bases in New Zealand, New Caledonia, the New Hebrides, and the Fijis to Guadalcanal.

As flagship of Rear Admiral Theodore Stark Wilkinson's 3rd Amphibious Force, George Clymer departed Guadalcanal 30 October for the invasion of Bougainville.

She returned to Port Purvis on Florida Island in the Solomons, on 3 November; and during the next two months she made three runs to Bougainville, carrying reinforcements and cargo from the Fijis and Guadalcanal.

George Clymer continued troop-carrying and supply runs in the Southwest Pacific until 4 June 1944 when she departed Guadalcanal for the invasion of the Marianas.

Steaming via Kwajalein, she operated off Saipan from 17 to 30 June while serving as flagship of Rear Admiral Lawrence Fairfax Reifsnider's Southern Attack Group.

After debarking assault troops, she served as receiving ship, boat pool tender, and medical station for the Southern Transport Group.

Underway again 15 September, George Clymer steamed via Eniwetok and Manus, Admiralties, to the Philippines, where she landed nearly 1,000 troops at Dulag 21 October during the battle of Leyte.

She returned to Manus 28 October; and, following a troop and cargo-carrying mission to New Britain and back, she sailed 11 November for the United States and arrived San Francisco 3 December for overhaul.

She departed Qingdao 5 August; embarked troops at Guam, and transported them via the Panama Canal to Morehead City, North Carolina, where she arrived 17 September.

She departed Yokosuka 1 April 1952; returned to the United States for 7 months; then sailed from San Diego 12 November for a third deployment off Korea under the command of CAPT Edward J. O'Donnell.

On 27 July 1953, as the armistice which brought an uncertain peace to Korea was signed at Panmunjom, she departed Yokosuka for the United States, arriving San Diego 22 August.

Capable of carrying combat-ready troops to any beach in the Western Pacific and Southeast Asia, she provided vital support to the Fleet's operations.