USS Josephine H. II (SP-245) was a United States Navy patrol vessel in commission from 1917 to 1918.

Josephine H. II was built as a civilian motorboat of the same name in 1912 by the Bosserdet Yacht and Engine Company.

The U.S. Navy acquired her from her owners, John R. Shuman et al., in July 1917 for World War I service as a patrol vessel.

She was commissioned on 3 August 1917 as USS Josephine H. II (SP-245).

She performed guard duty and regulated traffic on the Detroit River and in Lake St. Clair for the remainder of World War I. Josephine H. II was decommissioned on 29 November 1918.