The first USS Marie (SP-100) was an armed motorboat that served in the United States Navy as a patrol vessel from 1917 to 1919.

Marie was built as a civilian motorboat in 1912 by Seabury's at Morris Heights, New York.

The U.S. Navy acquired her on 28 April 1917 from her owner, O. M. Pynchon, for use as a patrol boat during World War I.

The Navy took delivery of her on 1 May 1917 and commissioned her on 15 June 1917 as USS Marie (SP-100).

On 6 August 1919, Marie was stricken from the Navy List.