USS Regis II (SP-1083) was a United States Navy patrol vessel in commission from 1917 to 1919.

Regis II was built as a private motor yacht or motorboat of the same name in 1902 for J. E. Kerr of Baltimore, Maryland, by Simon Martin.

In 1917, her owner loaned her to the U.S. Navy for use as a section patrol boat during World War I.

Assigned to the 5th Naval District, Regis II served on patrol duty in the harbor at Norfolk, Virginia, in Hampton Roads, and in the lower Chesapeake Bay through the end of World War I.

The Navy returned Regis II to her owner on 25 January 1919.