USS Sagamore was a Unadilla-class gunboat built on behalf of the United States Navy for service during the American Civil War.

On 26 November 1861, Sagamore received orders to report to Flag Officer William McKean for duty as part of the East Gulf Blockading Squadron which patrolled the waters off the coasts of Florida, Alabama, and Mississippi.

On 30 June 1862, Sagamore attacked Tampa, Florida, but withdrew after exchanging fire with a Confederate shore battery.

On 11 September, a landing party from Sagamore destroyed the salt works, which could produce 200 bushels a day, at St. Andrews Bay, Florida.

Sagamore next captured the blockade-running English schooner By George off Indian River, Florida on 1 December, with a cargo of coffee and sugar.

In 1870, she was demilitarized and sold to a civilian shipping firm operating scheduled services between Osaka and Tokyo.