The greatest alteration was the new tear-drop hull, pioneered by the conventionally powered USS Albacore, and designed for optimum performance underwater.
Nuclear power had already been employed on the Nautilus and the follow-on Skate class, but the 15,000 SHP plant was such an advance that it entirely changed a submarine's capability.
As earlier private inventors like John P. Holland had envisioned, the submarine was designed as having its natural environment underwater, and became capable of things never before seen.
The boat's motto was Radix Nova Tridentis, meaning "Root of the New Sea Power"; and correctly so, as every US attack submarine until 1988 (when the diving planes moved back to the bow on the improved Los Angeles class) turned out to follow the Skipjack's design.
After being launched 26 May 1958, Skipjack was soon dubbed the "world's fastest submarine", after setting the speed record on sea trials in March of the following year.
Skipjack commenced her 1961 operations by participating in two weeks of type training followed by anti-submarine warfare exercises through August, visiting Mayport, Florida, before returning to Groton.
In January 1962, Skipjack operated out of Key West, Florida, for two weeks before entering the Portsmouth Naval Shipyard in Maine for extensive overhaul, lasting four and one-half months.
Following her return to New London, Connecticut, the submarine operated locally prior to departing in October for duty in the Mediterranean with the Sixth Fleet.
During this tour, Skipjack participated in various fleet and NATO exercises and visited Toulon, France; and La Spezia and Naples, Italy, before returning to New London.
The highlight of 1964 was two months of duty with NATO forces, participating in exercises "Masterstroke" and "Teamwork" and visiting Le Havre, France, and the Isle of Portland, England, before returning to New London in October.
After devoting most of 1965 to training exercises, the submarine ended the year by entering the Charleston Naval Shipyard in South Carolina for an overhaul that lasted until 18 October 1966.
Skipjack then got underway for sea trials off Charleston, before joining Shark for four days of type training in the Jacksonville, Florida, area.
Early in February 1967, Skipjack got underway for sonar and weapon tests and then participated in Atlantic submarine exercises from March through June.
Following an extended deployment in October and November, the submarine returned to Norfolk to prepare for major operations of that year which she completed on 25 February 1968.
Highlights of 1971 were sound trials and weapons system tests at the Atlantic Fleet Range, Puerto Rico, from 25 January through 5 March and NATO exercise "Royal Night" from 15 September to 9 October.
After returning to Norfolk, Skipjack conducted several exercises with ASW aircraft flying from air bases in Virginia and North Carolina.
At the end 1973 Skipjack was transferred to the submarine base at Groton in preparation for a refueling overhaul at General Dynamics' Electric Boat Division.
During UNITAS, she engaged in ASW operations with ships of the Atlantic Fleet and from various South American Navies requiring she transit the Panama Canal into the Pacific and then return.
); Roosevelt Roads, Puerto Rico; Rodman, Panama; Callao, Peru; Manta, Ecuador; Puerta La Cruz, Venezuela; Barbados; St. Kitts; and Curaçao.
During this transit she stopped in Fort Lauderdale and Rodman again and then at San Diego, CA before arriving at Mare Island in late January 1981.
Skipjack left in September and visited the Naval Base in Puerto Rico; Caracas, Venezuela (anchored out); Cartagena, Colombia and then transited the Panama Canal.
Skipjack's authorization to dive expired in March 1989 since it was not cost efficient to inspect the hull in 1987 for a ship scheduled to be decommissioned.
From March thru June, Skipjack provided bridge training to students at the Submarine Officer Basic School in Groton, mostly running up and down the river.