USS Spicewood (AN-53/YN-72) was an Ailanthus-class net laying ship which served with the U.S. Navy in the South Pacific Ocean theatre of operations during World War II.

Spicewood was laid down as YN-72 on 25 May 1943 at Stockton, California, by the Pollock-Stockton Shipbuilding Company; redesignated AN-53 on 20 January 1944; launched on 6 December 1943; and commissioned on 7 April 1944.

The net layer completed shakedown training and post-shakedown availability by 19 June and towed fuel barge YO-92 from San Pedro, California, to Hawaii, arriving at Pearl Harbor on the 29th.

There she was assigned to the 14th Naval District and relieved the Coast Guard tug Balsam (WAGL-62) at the Phoenix Islands, located east of the Gilbert and Ellice groups.

Her name was struck from the Navy List on 12 March 1946, and her hulk was sold on 18 April 1947 to the Van Camp Seafood Company, Terminal Island, California.