Despite a fearsome antiaircraft barrage and repeated attacks by the numerically superior enemy fighter planes, Lt. Tweedy dove his aircraft to a perilously low altitude before releasing a bomb over the carrier.

On completion of her fitting out, Tweedy departed Boston, Massachusetts, on 1 March and steamed for Bermuda where she conducted shakedown exercises through the end of the month.

En route from Bermuda to Boston on 30 and 31 March, the destroyer escort conducted an unproductive 13-hour search for a German submarine known to be lurking in the coastal shipping lanes.

Assigned to the Naval Training Center, Miami, she operated off the Florida Keys, conducting indoctrination cruises for student officers and nucleus crews.

Occasionally putting in at Charleston, South Carolina, for repairs or alterations, she continued in this essential but inconspicuous role, supplying the fleets with trained personnel, into the early months of 1945.

Tweedy was the only destroyer escort to receive the full SCB 63 anti-submarine warfare conversion, including a new superstructure forward with four Hedgehogs mounted above the bridge, which was moved on the 01 level.

Following exercises out of Guantanamo Bay, Cuba, she finished out the year as a training ship for the Fleet Sonar School at Key West, Florida.

For the next three years, Tweedy conducted reserve training and midshipman cruises in addition to assignments at the Fleet Sonar School at Key West and participated in the annual Operation Springboard in the Caribbean.

Following refresher training, she was assigned the home port of Newport, Rhode Island, and commenced antisubmarine barrier duties in the Caribbean early in 1962.

On 12 June, as Tweedy steamed from Pensacola to Norfolk, Virginia, she came upon nine Cuban nationals in distress after two days at sea in an open, 14-foot boat.